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Molecular Pharmaceutics
Is the
emerging field of nanomedicine a breathtaking technological revolution
that promises remarkable new ways of diagnosing and treating diseases?
Or does it portend the release of dangerous nanoparticles, nanorobots or
nanoelectronic devices that will wreak havoc in the body? A new review
of more than 500 studies on the topic concludes that neither scenario is
likely. It appears in ACS' journal
Molecular Pharmaceutics.
Ruth Duncan and Rogerio
Gaspar explain that nanomedicine - the application of nanotechnology to
health care -often is overhyped as cure-alls or a potential danger. The
concept debuted with the visionary notion that robots and electronic
devices so tiny that dozens would fit across the width of a human hair
could be built and put into the human body to treat disease and repair
damaged organs. About 40 nano health care products actually are in use
and nano-sized drugs, drug delivery devices, imaging
agents, and other products are on the horizon.
The authors first
describe the history of nanomedicine, as well as many of the
nanomedicine products available today. Then, they offer suggestions for
how best to move a nanomedicine through the drug development process
with risks and benefits in mind. Finally, they identify key factors
critical for development of practical nanomedical technology that is
safe and effective.
The authors acknowledged funding from iMedUL and The Fundação para a Ciência e a Tecnologia.
Source: American Chemical Society